个人简介

魏树花，1992年出生，山东日照人，现任德州学院生物物理研究院讲师。2024年6月毕业于山东师范大学分析化学专业，博士研究生。以第一作者或通讯作者发表SCI论文9篇，相关研究工作发表在Analytical Chemistry、Biosensors and Bioelectronics、Chemical Engineering Journal、Sensors and Actuators: B. Chemical、Chemical Communications和Talanta国际专业期刊。

主要研究领域：

1、生化分析和生物医学研究。

2、新型荧光生物传感器的构建及其临床应用研究。

3、单分子检测与成像及其临床应用研究。

部分论文：

1、Dongling Li,a Wenliang Ma,b Shu-hua Wei,c Shi-cai Xu,c Juan Hu,a,* Jinqiu Tao,b,* and Chun-yang Zhang a,* "A programmable DNAzyme-activated entropy- driven logic circuit for high-contrast imaging of piRNAs and discrimination of cancer cells" Biosensors and Bioelectronics 2026, 305, 118687.

2、Shu-hua Wei,a,† Lin-lin Song,b,† Rui Wang,a Wan-ling Cui,a Rui-zhi Wang,a Yong-cun Yan,a Yue Zhao,a Shi-cai Xu*a and Chun-yang Zhang*c "Construction of a ligation-controlled light-up fluorescent aptasensor for sensitive detection of cancer-related circRNAs in clinical tissues" Sensors and Actuators B: Chemical 2026, 458, 139772.

3、Xiao-wen Liu a,1, Yun Han b,1, Shu-hua Wei a,1, Bao-mei Zhou b, Xiaoran Zou a,*, Chun-yang Zhang b.* "Construction of a self-priming hairpin probe for rapid and isothermally one-step detection of multiple long noncoding RNAs in living cells and tissues." Chemical Engineering Journal, 2025, 505, 159600.

4、Zichen Jiao a,1, Ning-ning Zhao b,1, Shu-hua Wei c,*, Dong-ling Li d, Tao Wang a,*, Chun-yang Zhang d,*. "Construction of a light-up multicolor fluorescent aptasensor for simultaneous measurement of multiple miRNAs in breast cancer tissues." Sensors and Actuators B: Chemical 2025, 433, 137542.

5、Fei Ma a, Qian Han a, Shu-hua Wei b,*, Chun-yang Zhang a,** Flap cleavage-directed promoter reconstitution and transcription reactivation for label-free and sensitive detection of flap endonuclease 1 activity. Talanta, 2025, 295, 128313.

6、Shu-hua Wei,∥ Jinping Hu,∥ Zhimei Sheng,∥ Qian Zhang, Jie Zhang, Baogang Zhang,* Meng Liu,* and Chun-yang Zhang*. Construction of Fluorescent G-Quadruplex Nanowires for Label-Free and Accurate Monitoring of Circular RNAs in Breast Cancer Cells and Tissues with Low Background. Analytical Chemistry, 2023, 96(1), 599-605.

7、Shu-hua Wei,§ Meng Liu,§ Juan Hu,* and Chun-yang Zhang*."Target-initiated cascade signal amplification lights up a G-Quadruplex for a label-free detection of circular ribonucleic acids." Analytical Chemistry, 2022, 94(25), 9193-9200.

8、Fei Ma,‡ Shu-hua Wei,‡ and Chun-yang Zhang*."Construction of a robust entropy-driven DNA nanomachine for single-molecule detection of rare cancer cells." Analytical chemistry, 2019, 91 (12), 7505-7509.

9、Fei Ma,‡a Shu-hua Wei,‡a Junhong Leng,‡b Bo Tang *a and Chun-yang Zhang*a A simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions." Chemical Communications, 2018, 54 (20), 2483-2486.